000			04525nab a2200397 c 4500
001			vtls000574915
003			RU-ToGU
005			20230319211206.0
007			cr |
008			170426|2016 enk s a eng dd
024	7		_a10.1016/S2215-0366(15)00358-2 _2doi
035			_ato000574915
040			_aRU-ToGU _brus _cRU-ToGU
245	1	0	_aMental health resilience in the adolescent offspring of parents with depression: a prospective longitudinal study _cS. Collishaw, G. Hammerton, L. Mahedy [et.al.]
504			_aБиблиогр.: 36 назв.
520	3		_aBackground Young people whose parents have depression have a greatly increased risk of developing a psychiatric disorder, but poor outcomes are not inevitable. Identification of the contributors to mental health resilience in young people at high familial risk is an internationally recognised priority. Our objectives were to identify protective factors that predict sustained good mental health in adolescents with a parent with depression and to test whether these contribute beyond what is explained by parent illness severity. Methods The Early Prediction of Adolescent Depression study (EPAD) is a prospective longitudinal study of offspring of parents with recurrent depression. Parents with recurrent major depressive disorder, co-parents, and offspring (aged 9–17 years at baseline) were assessed three times over 4 years in a community setting. Offspring outcomes were operationalised as absence of mental health disorder, subthreshold symptoms, or suicidality on all three study occasions (sustained good mental health); and better than expected mental health (mood and behavioural symptoms at follow-up lower than predicted given severity of parental depression). Family, social, cognitive, and health behaviour predictor variables were assessed using interview and questionnaire measures. Findings Between February and June, 2007, we screened 337 families at baseline, of which 331 were eligible. Of these, 262 completed the three assessments and were included in the data for sustained mental health. Adolescent mental health problems were common, but 53 (20%) of the 262 adolescents showed sustained good mental health. Index parent positive expressed emotion (odds ratio 191 [95% CI 131–279]; p=0001), co-parent support (190 [138–262]; p<00001), good-quality social relationships (207 [135–318]; p=0001), self-efficacy (149 [105–211]; p=003), and frequent exercise (296 [126–692]; p=001) were associated with sustained good mental health. Analyses accounting for parent depression severity were consistent, but frequent exercise only predicted better than expected mood-related mental health (β=–022; p=00004) not behavioural mental health, whereas index parents' expression of positive emotions predicted better than expected behavioural mental health (β=–016; p=001) not mood-related mental health. Multiple protective factors were required for offspring to be free of mental health problems (zero or one protective factor, 4% sustained good mental health; two protective factors, 10%; three protective factors, 13%, four protective factors, 38%; five protective factors, 48%). Interpretation Adolescent mental health problems are common, but not inevitable, even when parental depression is severe and recurrent. These findings suggest that prevention programmes will need to enhance multiple protective factors across different domains of functioning. Funding Sir Jules Thorn Charitable Trust, Economic and Social Research Council.
653			_aпсихическое здоровье
653			_aподростки
653			_aдепрессии
655		4	_aстатьи в журналах _9879358
700	1		_aCollishaw, Stephan _9286137
700	1		_aMahedy, Liam _9286132
700	1		_aSellers, Ruth _9459409
700	1		_aOwen, Michael J. _9315293
700	1		_aCraddock, Nicholas _9476265
700	1		_aThapar, Ajay K. _9476266
700	1		_aHarold, Gordon T. _9286134
700	1		_aRice, Frances _9459410
700	1		_aThapar, Anita _9286135
700	1		_aHammerton, Gemma _9286131
773	0		_tThe lancet psychiatry _d2016 _gVol. 3, № 1. P. 49-57 _x2215-0374
852	4		_aRU-ToGU
856	7		_uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000574915
908			_aстатья
999			_c423966