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Global tests evaluating the functional condition of hemostasis M. A. Solovyev, I. I. Tutrin, V. V. Udut [et.al.]

Contributor(s): Solovyev, M. A | Udut, Vladimir V | Borodulina, E. V | Turenko, A. V | Tutrin, I. IMaterial type: ArticleArticleSubject(s): гемокоагуляция | низкочастотная тромбоэластография | гемостатический потенциал | система регуляции агрегатного состояния крови | цельная кровьGenre/Form: статьи в журналах Online resources: Click here to access online In: Journal of clinical & experimental pharmacology Vol. 5, № 4. P. 1000178-1-1000178-4Abstract: Control of effectiveness of global tests evaluation of the functional state regulation of blood aggregation provided an opportunity to obtain timely information about the I-II and III phases of hemostasis while using native substrate - whole blood. Ex vivo, registered during hemocoagulation of changing the viscous characteristics of whole blood, allowed to formulate the concept of fibrinogenesis permanence as in vivo existing process, defining proper hemostatic potential – integrative characteristic of the entire cycle of hemocoagulation, ensuring necessary blood fluidity and restricting extravasation of its components in case of defecting its permeability or damaging its vascular wall.
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Control of effectiveness of global tests evaluation of the functional state regulation of blood aggregation provided an opportunity to obtain timely information about the I-II and III phases of hemostasis while using native substrate - whole blood. Ex vivo, registered during hemocoagulation of changing the viscous characteristics of whole blood, allowed to formulate the concept of fibrinogenesis permanence as in vivo existing process, defining proper hemostatic potential – integrative characteristic of the entire cycle of hemocoagulation, ensuring necessary blood fluidity and restricting extravasation of its components in case of defecting its permeability or damaging its vascular wall.

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