Изучение специфической активности прототипа антимикотика на основе клотримазола Ю. Д. Разгуляева, Д. А. Федоришин
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ArticleContent type: Текст Media type: электронный Other title: Study of specific activity of antimicotic prototype based on clotrimazole [Parallel title]Subject(s): фунгициды | оппортунистические инфекции | клотримазол | антигрибные препараты | экспериментальные исследованияGenre/Form: статьи в сборниках Online resources: Click here to access online
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Перспективы развития фундаментальных наук. Т. 4 : сборник научных трудов XVII Международной конференции студентов, аспирантов и молодых ученых, Россия, Томск, 21-24 апреля 2020 г Т. 4 : Биология и фундаментальная медицина. С. 73-75Abstract: Clotrimazole is an antifungal agent for topical application from the group of imidazole derivatives. However, the high adaptability offungi to old antimycotics forces us to look for new compounds with antifungal activity. Therefore, the synthesis of coordination compounds based on clotrimazole is a promising direction for the search for new antimycotics. In this study, a prototype antimycotic based on clotrimazole was studied. The high antifungal activity of the new compound has been established. The synergistic action of ligands in this composition has been established.
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Clotrimazole is an antifungal agent for topical application from the group of imidazole derivatives. However, the high adaptability offungi to old antimycotics forces us to look for new compounds with antifungal activity. Therefore, the synthesis of coordination compounds based on clotrimazole is a promising direction for the search for new antimycotics. In this study, a prototype antimycotic based on clotrimazole was studied. The high antifungal activity of the new compound has been established. The synergistic action of ligands in this composition has been established.
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