Sub-wavelength-resolution imaging of biological tissues using THz solid immersion microscopy N. V. Chernomyrdin, A. S. Kucheryavenko, G. S. Kolontaeva [et al.]
Material type:
ArticleSubject(s): терагерцовое излучение | биологические ткани | терагерцовая микроскопия | субволновое пространственное разрешениеGenre/Form: статьи в сборниках Online resources: Click here to access online
In:
International Conference Laser Optics 2018 (ICLO 2018), St. Petersburg, Russia, 4-8 June, 2018 : proceedings P. 519Abstract: We have proposed a method of THz solid
immersion microscopy, which yields imaging soft biological
tissues with the sub-wavelength resolution up to 0.2-wavelengths.
To achieve this advanced resolution, it employs a solid immersion
phenomenon – i.e. a reduction in the dimensions of the THz beam
caustic by its formation on a small distance behind the medium
featuring high refractive index. We have assembled an
experimental setup, which realizes the principles of the THz solid
immersion microscopy, and proposed an approach for handling
the soft tissue at the object plane. This setup uses a backwardwave
oscillator, as a source of continuous-wave THz radiation,
and a Golay cell, as a detector of the THz field intensity. We have
examined the resolution of the THz solid immersion microscopy
using both numerical simulations and experimental studies.
Finally, in order to highlight the prospective of the proposed THz
imaging modality, we have applied the experimental setup for
imaging of representative examples of biological tissues.
Библиогр.: 13 назв.
We have proposed a method of THz solid
immersion microscopy, which yields imaging soft biological
tissues with the sub-wavelength resolution up to 0.2-wavelengths.
To achieve this advanced resolution, it employs a solid immersion
phenomenon – i.e. a reduction in the dimensions of the THz beam
caustic by its formation on a small distance behind the medium
featuring high refractive index. We have assembled an
experimental setup, which realizes the principles of the THz solid
immersion microscopy, and proposed an approach for handling
the soft tissue at the object plane. This setup uses a backwardwave
oscillator, as a source of continuous-wave THz radiation,
and a Golay cell, as a detector of the THz field intensity. We have
examined the resolution of the THz solid immersion microscopy
using both numerical simulations and experimental studies.
Finally, in order to highlight the prospective of the proposed THz
imaging modality, we have applied the experimental setup for
imaging of representative examples of biological tissues.
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