Секретируемые биомаркеры макрофагов при различных типах рака Т. С. Сударских, М. А. Ракина, Е. Г. Шаповалова
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ArticleContent type: Текст Media type: электронный Other title: Secreted macrophage biomarkers in various types of cancer [Parallel title]Subject(s): опухолеассоциированные макрофаги | биомаркеры | экспериментальные исследованияGenre/Form: статьи в сборниках Online resources: Click here to access online
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Перспективы развития фундаментальных наук. Т. 4 : сборник научных трудов XIX Международной конференции студентов, аспирантов и молодых ученых, 26-29 апреля 2022 г Т. 4 : Биология и фундаментальная медицина. С. 66-68Abstract: Tumor-associated macrophages (TAMs) are key innate immune cells in tumor microenvironment (TME) that regulate growth of primary tumors, antitumor adaptive immune response, tumor angiogenesis, extracellular matrix remodeling, intravasation in the vasculature, extravasation in metastatic sites [1]. TAMs are highly heterogeneous cells, and their variability strongly depends on cancer type, stage and intratumor heterogeneity. In this work, secreted biomarkers of macrophages in various types of cancer were studied. The differences in secreted profile of TAMs in breast, rectal, lung, ovarian and prostate cancers were revealed.
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Tumor-associated macrophages (TAMs) are key innate immune cells in tumor microenvironment (TME) that regulate growth of primary tumors, antitumor adaptive immune response, tumor angiogenesis, extracellular matrix remodeling, intravasation in the vasculature, extravasation in metastatic sites [1]. TAMs are highly heterogeneous cells, and their variability strongly depends on cancer type, stage and intratumor heterogeneity. In this work, secreted biomarkers of macrophages in various types of cancer were studied. The differences in secreted profile of TAMs in breast, rectal, lung, ovarian and prostate cancers were revealed.
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