The influence of cisplatin on transcriptional profile of tumor-associated macrophages of breast cancer and colon cancer I. V. Larionova, L. Tengfei, A. M. Kiselev [et.al.]
Material type:
ArticleSubject(s): опухоль-ассоциированные макрофаги | химиотерапия | цисплатин | онкологические заболевания | секвенирование следующего поколенияGenre/Form: статьи в сборниках Online resources: Click here to access online
In:
The 22nd International Charles Heidelberger symposium on cancer research : proceedings of the International symposium, 17-19 September 2018 P. 62-63Abstract: In the present study we demonstrated the whole transcriptome analysis of model tumor-associated
macrophages (TAM) of breast and colon cancer with using next-generation sequencing data.
We identified the most significantly increased and down-regulated genes as well as differentially
expressed genes for breast and cancer TAM. Our results showed that TAM can be reprogrammed
by chemotherapeutic agents and obtain mostly pro-inflammatory program.
Библиогр.: 4 назв.
In the present study we demonstrated the whole transcriptome analysis of model tumor-associated
macrophages (TAM) of breast and colon cancer with using next-generation sequencing data.
We identified the most significantly increased and down-regulated genes as well as differentially
expressed genes for breast and cancer TAM. Our results showed that TAM can be reprogrammed
by chemotherapeutic agents and obtain mostly pro-inflammatory program.
There are no comments on this title.