Sparing surgery with the use of TiNi-based endografts in larynx cancer patients M. R. Muhamedov, D. E. Kulbakin, V. E. Gunther [et.al.]
Material type:
ArticleSubject(s): эндопротезы | рак гортани | никелид титанаGenre/Form: статьи в журналах Online resources: Click here to access online
In:
Journal of surgical oncology Vol. 111. P. 231-236Abstract: Background and Objectives
Purpose of this study was to improve a technique of sparing surgery in patients with laryngeal cancer by using TiNi-based endografts and to achieve well functional and oncological results after laryngectomy.
Methods
Totally 120 patients with laryngeal cancer were observed (T2–3N0–1M0). We have developed a method of laryngeal reconstruction using TiNi-based endografts. All endografts show the superelastic behavior recovering the shape. All patients have undergone different types of sparing surgeries with simultaneous replacement with endografts.
Results
Voice function was completely saved in 112 cases and partially in 8 ones. Respiratory function was fully restored in 106 patients. The protective function of the larynx was achieved in 116 patients.
Conclusion
The technique allowed to achieve well oncological (the 5-year and overall recurrence-free survival rates of all 120 patients were 83% and 76%, respectively) and functional (larynx function was saved in 93% of cases) outcomes after extensive and subtotal resections in patients with locally distributed larynx cancer.
Библиогр.: 34 назв.
Background and Objectives
Purpose of this study was to improve a technique of sparing surgery in patients with laryngeal cancer by using TiNi-based endografts and to achieve well functional and oncological results after laryngectomy.
Methods
Totally 120 patients with laryngeal cancer were observed (T2–3N0–1M0). We have developed a method of laryngeal reconstruction using TiNi-based endografts. All endografts show the superelastic behavior recovering the shape. All patients have undergone different types of sparing surgeries with simultaneous replacement with endografts.
Results
Voice function was completely saved in 112 cases and partially in 8 ones. Respiratory function was fully restored in 106 patients. The protective function of the larynx was achieved in 116 patients.
Conclusion
The technique allowed to achieve well oncological (the 5-year and overall recurrence-free survival rates of all 120 patients were 83% and 76%, respectively) and functional (larynx function was saved in 93% of cases) outcomes after extensive and subtotal resections in patients with locally distributed larynx cancer.
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