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Microbicides for Prevention of HIV Infection electronic resource edited by Jeremy Nuttall.

Contributor(s): Nuttall, Jeremy [editor.] | SpringerLink (Online service)Material type: TextTextSeries: Current Topics in Microbiology and ImmunologyPublication details: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014Description: IX, 179 p. 12 illus., 6 illus. in color. online resourceContent type: text Media type: computer Carrier type: online resourceISBN: 9783662445969Subject(s): medicine | Vaccines | Pharmaceutical technology | Medical virology | Biomedicine | Virology | Vaccine | Pharmaceutical Sciences/TechnologyDDC classification: 616.9101 LOC classification: QR355-502Online resources: Click here to access online
Contents:
Candidate Microbicides and Their Mechanisms of Action -- Microbicide Dosage Forms -- Preclinical Safety Evaluation -- Clinical Safety and Pharmacology Trial -- Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials -- Rectal Microbicide Development -- Developing Regulatory Strategy for Microbicides -- Preparing for Microbicide Introduction, Rollout and Sustained Access.
In: Springer eBooksSummary: One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
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Candidate Microbicides and Their Mechanisms of Action -- Microbicide Dosage Forms -- Preclinical Safety Evaluation -- Clinical Safety and Pharmacology Trial -- Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials -- Rectal Microbicide Development -- Developing Regulatory Strategy for Microbicides -- Preparing for Microbicide Introduction, Rollout and Sustained Access.

One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.

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