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Measurement of tissue optical properties in the context of tissue optical clearing A. N. Bashkatov, K. V. Berezin, K. N. Dvoretskiy [et al.]

Contributor(s): Berezin, Kirill V | Dvoretski, Konstantin N | Chernavina, Maria L | Genina, Elina A | Genin, Vadim D | Kochubey, Vyacheslav I | Lazareva, Ekaterina N | Pravdin, Alexander B | Shvachkina, Marina E | Bashkatov, Alexey N | Dyachenko, Polina A | Tuchina, Daria K | Yakovlev, Dmitry D | Yakovlev, Dmitry A | Yanina, Irina Yu | Zhernovaya, Olga S | Tuchin, Valery VMaterial type: ArticleArticleContent type: Текст Media type: электронный Subject(s): биологические ткани | кожа | жировая ткань | оптические свойства | показатель преломления | поляризация | кровеносные сосуды | микроциркуляция | молекулярное моделированиеGenre/Form: статьи в журналах Online resources: Click here to access online In: Journal of biomedical optics Vol. 23, № 9. P. 091416-1-091416-31Abstract: Nowadays, dynamically developing optical (photonic) technologies play an ever-increasing role in medicine. Their adequate and effective implementation in diagnostics, surgery, and therapy needs reliable data on optical properties of human tissues, including skin. This paper presents an overview of recent results on the measurements and control of tissue optical properties. The issues reported comprise a brief review of optical properties of biological tissues and efficacy of optical clearing (OC) method in application to monitoring of diabetic complications and visualization of blood vessels and microcirculation using a number of optical imaging technologies, including spectroscopic, optical coherence tomography, and polarization- and speckle-based ones. Molecular modeling of immersion OC of skin and specific technique of OC of adipose tissue by its heating and photodynamic treatment are also discussed.
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Nowadays, dynamically developing optical (photonic) technologies play an ever-increasing role in medicine. Their adequate and effective implementation in diagnostics, surgery, and therapy needs reliable data on optical properties of human tissues, including skin. This paper presents an overview of recent results on the measurements and control of tissue optical properties. The issues reported comprise a brief review of optical properties of biological tissues and efficacy of optical clearing (OC) method in application to monitoring of diabetic complications and visualization of blood vessels and microcirculation using a number of optical imaging technologies, including spectroscopic, optical coherence tomography, and polarization- and speckle-based ones. Molecular modeling of immersion OC of skin and specific technique of OC of adipose tissue by its heating and photodynamic treatment are also discussed.

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