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Macrophage polarization markers of blood monocytes in patients with breast cancer M. Patysheva, M. N. Stakheyeva, N. A. Tarabanovskaya [et.al.]

Contributor(s): Patysheva, Marina R | Tarabanovskaya, Natalia A | Grigoryeva, Evgeniya S | Slonimskaya, Elena M | Kzhyshkowska, Julia G | Cherdyntseva, Nadezhda V | Stakheyeva, Marina NMaterial type: ArticleArticleSubject(s): хитиназоподобные белки | рак молочной железы | поляризация моноцитовGenre/Form: статьи в сборниках Online resources: Click here to access online In: The 22nd International Charles Heidelberger symposium on cancer research : proceedings of the International symposium, 17-19 September 2018 P. 82-84Abstract: Polarized monocytes can have diagnostic value in breast cancer, including a triple negative subtype. We examined the markers of M2- polarization of monocytes: CD163 and stabilin1 and the recently described chitinase-like proteins: SI-CLP, YLK39, YLK40, in breast cancer patients and healthy volunteers. The features of polarized monocytes in breast cancer were revealed depending on the molecular subtype of the tumor.
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Polarized monocytes can have diagnostic value in breast cancer, including a triple negative
subtype. We examined the markers of M2- polarization of monocytes: CD163 and stabilin1 and the
recently described chitinase-like proteins: SI-CLP, YLK39, YLK40, in breast cancer patients and
healthy volunteers. The features of polarized monocytes in breast cancer were revealed depending
on the molecular subtype of the tumor.

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