TY  - SER
AU  - Vlassov,Valentin V.
AU  - Ponomaryova,Anastasia A.
AU  - Zaporozhchenko,Ivan A.
AU  - Morozkin,Evgeny S.
AU  - Cherdyntseva,Nadezhda V.
AU  - Laktionov,Pavel P.
AU  - Rykova,Elena Yu
TI  - Circulating microRNAs in lung cancer: prospects for diagnosis,  prognosis, and prediction of antitumor treatment efficacy
KW  - рак легких
KW  - опухолевые маркеры
KW  - циркулирующие микроРНК
KW  - статьи в журналах
N1  - Библиогр.: 39 назв
N2  - The review considers the main techniques to extract microRNA (miRNA) from various biological fluids (in particular, the serum and plasma), approaches to the analysis of miRNA concentration and composition, and methods to normalize the results in data analyses. Advantages and drawbacks of the methods are described. Special attention is given to circulating miRNAs, which can be used as markers for minimally invasive diagnosis, prediction of antitumor treatment efficacy, and disease prognosis in lung cancer. The review discusses the prospects and limitations that arise as the clinical significance is evaluated for miRNAs as potential tumor markers and a better understanding is gained for the roles various miRNAs play in the pathogenesis of lung cancer
UR  - http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000577973
ER  -