TY  - SER
AU  - Zuhayri,Hala
AU  - Nikolaev,Viktor V.
AU  - Knyazkova,Anastasia I.
AU  - Lepekhina,Tatiana B.
AU  - Krivova,Natalya A.
AU  - Tuchin,Valery V.
AU  - Kistenev,Yury V.
TI  - In vivo quantification of the effectiveness of topical low-dose photodynamic therapy in wound healing using two-photon microscopy
KW  - лечение раны
KW  - фотодинамическая терапия
KW  - низкие дозы
KW  - фотосенсибилизаторы
KW  - двухфотонная микроскопия
KW  - генерация второй гармоники
KW  - автофлуоресценция
KW  - статьи в журналах
N1  - Библиогр.: 61 назв
N2  - The effect of low-dose photodynamic therapy on in vivo wound healing with topical application of 5-aminolevulinic acid and methylene blue was investigated using an animal model for two laser radiation doses (1 and 4 J/cm2). A second-harmonic-generation-to-auto-fluorescence aging index of the dermis (SAAID) was analyzed by two-photon microscopy. SAAID measured at 60–80 μm depths was shown to be a suitable quantitative parameter to monitor wound healing. A comparison of SAAID in healthy and wound tissues during phototherapy showed that both light doses were effective for wound healing; however, healing was better at a dose of 4 J/cm2
UR  - http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000926715
ER  -