TY - SER AU - Zyuzkov,Gleb N. AU - Udut,Elena V. AU - Miroshnichenko,L.A. AU - Chaikovsky,A.V. AU - Simanina,E.V. AU - Danilets,M.G. AU - Minakova,M.Yu AU - Demkin,V.P. AU - Udut,Vladimir V. AU - Zhdanov,Vadim V. AU - Tolstikova,T.G. AU - Shults,E.E. AU - Agafonov,V.I. AU - Dygai,Alexander M. TI - Role of NF-κB/IKK-dependent signaling in functional stimulation of mesenchymal progenitor cells by alkaloid songorine KW - мезенхимальные клетки KW - внутриклеточные сигнальные пути KW - клетки-предшественники KW - статьи в журналах N1 - Библиогр.: 15 назв N2 - We studied the role of NF-κB/IKK-mediated signaling in the stimulation of growth potential of mesenchymal progenitor cells by alkaloid songorine in vitro. Specific NF-κB inhibitor oridonin abolished activation of proliferation and differentiation of progenitor cells. Aurothiomalate, a selective blocker of IKK-2, also suppressed mitotic activity of fibroblast precursors, but had no effect on the rate of the differentiation UR - http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000578111 ER -