TY  - BOOK
AU  - Chhatwal,G.Singh
ED  - SpringerLink (Online service)
TI  - Host-Pathogen Interactions in Streptococcal Diseases
T2  - Current Topics in Microbiology and Immunology,
SN  - 9783642363405
AV  - QR46 
U1  - 616.9041 23
PY  - 2013///
CY  - Berlin, Heidelberg
PB  - Springer Berlin Heidelberg, Imprint: Springer
KW  - medicine
KW  - Immunology
KW  - microbiology
KW  - Vaccines
KW  - Public health
KW  - Bacteriology
KW  - Biomedicine
KW  - Medical Microbiology
KW  - Vaccine
KW  - Molecular Medicine
KW  - Public Health
N1  - Group A Streptococcal Diseases and Their Global Burden -- Molecular Markers for the Study of Streptococcal Epidemiology -- Epidemiology and Pathogenicity of Zoonotic Streptococci -- Adherence and Invasion of Streptococci to Eukaryotic Cells and Their Role in Disease Pathogenesis -- Common Regulators of Virulence in Streptococci -- Host-Pathogen Interactions in Streptococcal Immune Sequelae -- Immunopathogenesis of Streptococcal Deep Tissue Infections -- Modulation of the Coagulation System During Severe Streptococcal Disease -- Group A Streptococcal Vaccine Candidates: Potential for the Development of a Human Vaccine -- Clinical Management of the Most Common Group A β-Hemolytic Streptococcal Infections
N2  - Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases
UR  - http://dx.doi.org/10.1007/978-3-642-36340-5
ER  -