Differential diagnosis of paraffin-embedded tissues by IR-THz spectroscopy and machine learning Y. V. Kistenev, A. V. Borisov, A. I. Knyazkova и др.
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ArticleContent type: Текст Media type: электронный Subject(s): биопсия тканей | терагерцовая спектроскопия | оптическая когерентность | томография | магнитно-резонансная микроскопия | онкологияGenre/Form: статьи в журналах Online resources: Click here to access online
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Proceedings of SPIE Vol. 11363 : Tissue optics and photonics. P. 113630J-1-113630J-7Abstract: The ability of diagnostics of melanoma and nevus based on spectral analysis of paraffin-embedded tissues in the 0.3-1.5 terahertz (THz) range has been carried out. The principal component analysis was applied to reduce the dimension of the feature space. A comparison of these spectra shows evident differences between samples. The possibility of applying the optical clearing to paraffin-embedded tissue for improving the visualization of the internal structure of tissue for diagnostic and research purposes is shown. In the studies, a sufficiently strong effect of optical clearing of paraffin-embedded muscle was obtained (63%).
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The ability of diagnostics of melanoma and nevus based on spectral analysis of paraffin-embedded tissues in the 0.3-1.5 terahertz (THz) range has been carried out. The principal component analysis was applied to reduce the dimension of the feature space. A comparison of these spectra shows evident differences between samples. The possibility of applying the optical clearing to paraffin-embedded tissue for improving the visualization of the internal structure of tissue for diagnostic and research purposes is shown. In the studies, a sufficiently strong effect of optical clearing of paraffin-embedded muscle was obtained (63%).
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