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Exogenous agent diffusivity in tissues as a biomarker of diabetes mellitus pathology D. K. Tuchina, A. N. Bashkatov, A. B. Bucharskaya, V. V. Tuchin

Contributor(s): Bashkatov, Alexey N | Bucharskaya, Alla B | Tuchin, Valery V | Tuchina, Daria KMaterial type: ArticleArticleSubject(s): глицерин | биомаркеры | аллоксановый диабет | миокардGenre/Form: статьи в журналах Online resources: Click here to access online In: Proceedings of SPIE Vol. 10877 : Dynamics and fluctuations in biomedical photonics XVI. P. 108770X-1-108770X-7Abstract: The study offers a possibility to use such biocompatible chemical as glycerol as a biomarker for early diagnostics of diabetes mellitus complications, in particular, for assessing the degree of myocardial lesion evidence by the stage of skin glycation during diabetes development and treatment. The study was aimed to find the difference in glycerol permeability through rat soft tissues of control and diabetic groups in order to show the possibility of glycerol usage as a biomarker of diabetes impact on different organs. The investigation presents transition the experimental studies from ex vivo to in vivo conditions.
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The study offers a possibility to use such biocompatible chemical as glycerol as a biomarker for early diagnostics of diabetes mellitus complications, in particular, for assessing the degree of myocardial lesion evidence by the stage of skin glycation during diabetes development and treatment. The study was aimed to find the difference in glycerol permeability through rat soft tissues of control and diabetic groups in order to show the possibility of glycerol usage as a biomarker of diabetes impact on different organs. The investigation presents transition the experimental studies from ex vivo to in vivo conditions.

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