Исследование лимфедемы методом многофотонной микроскопии высокого разрешения В. В. Николаев, А. С. Курочкина, Д. А. Вражнов
Material type:
ArticleOther title: Research on lymphedema by method of high-resolution multiphoton microscopy [Parallel title]Subject(s): лимфедема | многофотонная микроскопия | автофлуоресценция | лимфатическая системаGenre/Form: статьи в сборниках Online resources: Click here to access online
In:
Перспективы развития фундаментальных наук. Т. 4 : сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, 24-27 апреля 2018 г Т. 4 : Биология и фундаментальная медицина. С. 113-115Abstract: In this paper results of iv-vivo measurements for healthy volunteers and people, with verified diagnosis of lymphedema, obtained with two-photon tomography with FLIM mode on MPTflex equipment (JenLab GmbH) are presented. In the study, eight healthy people and eight people with lymphedema disease participated. The papillary layer of the skin was analyzed at a depth of about 100 pm. In the course of the study, a small redistribution of autofluorescence lifetimes was observed for healthy volunteers and people with lymphedema disease. However, the main component composition in similar parts of the papillary dermis don’t not change significantly. This allows to make assumption that as a result of the development of the disease, structural changes occur that do not significantly affect the component composition of the tissue.
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In this paper results of iv-vivo measurements for healthy volunteers and people, with verified diagnosis of lymphedema, obtained with two-photon tomography with FLIM mode on MPTflex equipment (JenLab GmbH) are presented. In the study, eight healthy people and eight people with lymphedema disease participated. The papillary layer of the skin was analyzed at a depth of about 100 pm. In the course of the study, a small redistribution of autofluorescence lifetimes was observed for healthy volunteers and people with lymphedema disease. However, the main component composition in similar parts of the papillary dermis don’t not change significantly. This allows to make assumption that as a result of the development of the disease, structural changes occur that do not significantly affect the component composition of the tissue.
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