Diagnostics of oral lichen planus based on analysis of volatile organic compounds in saliva Y. Kistenev, A. Borisov, A. Shapovalov [et.al.]
Material type:
ArticleSubject(s): терагерцовая спектроскопия | спектральный анализ слюны | оральный лишайниковый планGenre/Form: статьи в журналах Online resources: Click here to access online
In:
Proceedings of SPIE Vol. 10063 : Dynamics and fluctuations in biomedical photonics XIV, 29–30 January 2017, San Francisco, California, United States. P. 100630R-1-100630R-7Abstract: The ability of diagnostics of oral lichen planus (OLP) based on spectral analysis of saliva using the THz spectroscopy is presented. The study included 8 patients with clinically proven OLP. The comparison group consisted of 8 healthy volunteers. Absorption spectra of the saliva was measured using time-domain spectrometer T-spec (EXPLA) in the range 0.2-3THz and have been considered as the feature vectors of the state. The spatial distribution of the objects under study in the feature space was analyzed using principle component analysis. The groups under study were shown to separate in full. Thus, the saliva analysis by the THz spectroscopy technique can be potentially used as a method of noninvasive diagnostics of the OLP.
Библиогр.: 13 назв.
The ability of diagnostics of oral lichen planus (OLP) based on spectral analysis of saliva using the THz spectroscopy is presented. The study included 8 patients with clinically proven OLP. The comparison group consisted of 8 healthy volunteers. Absorption spectra of the saliva was measured using time-domain spectrometer T-spec (EXPLA) in the range 0.2-3THz and have been considered as the feature vectors of the state. The spatial distribution of the objects under study in the feature space was analyzed using principle component analysis. The groups under study were shown to separate in full. Thus, the saliva analysis by the THz spectroscopy technique can be potentially used as a method of noninvasive diagnostics of the OLP.
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