Effect of silver additive on physicochemical properties of hydroxyapatite applied to reconstructive surgery I. V. Zhuk, L. A. Rasskazova, N. M. Korotchenko
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ArticleSubject(s): реконструктивная хирургия | гидроксиапатит | физико-химические свойства | сереброGenre/Form: статьи в журналах Online resources: Click here to access online
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AIP Conference Proceedings Vol. 1688. P. 060003-1-060003-6Abstract: The effect of silver adding to hydroxyapatite (HA) in its solubility in physiological solution and biological activity was investigated. Samples of HA containing silver (AgHA) obtained by liquid-phase method in the conditions of microwave exposure. Solubility (CCa2+·103, mol/l) of the powders AgHA was determined by chemical methods according trilonometric titration of the calcium ions in physiological solution at 25 and 37 °C. To investigate the biological activity of the samples, a series of experiments on the formation of the calcium-phosphate layer on the surface of the SBF-solution at 37 °C for 28 days. Electronic micrographs of samples taken at the end of each 7 days of the experiment, indicate the formation of calcium-phosphate layer (CPL) in the samples, the kinetics of which is shown as a function of cumulative concentrations of calcium and magnesium ions from time.
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The effect of silver adding to hydroxyapatite (HA) in its solubility in physiological solution and biological activity was investigated. Samples of HA containing silver (AgHA) obtained by liquid-phase method in the conditions of microwave exposure. Solubility (CCa2+·103, mol/l) of the powders AgHA was determined by chemical methods according trilonometric titration of the calcium ions in physiological solution at 25 and 37 °C. To investigate the biological activity of the samples, a series of experiments on the formation of the calcium-phosphate layer on the surface of the SBF-solution at 37 °C for 28 days. Electronic micrographs of samples taken at the end of each 7 days of the experiment, indicate the formation of calcium-phosphate layer (CPL) in the samples, the kinetics of which is shown as a function of cumulative concentrations of calcium and magnesium ions from time.
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