Xenon as a transdermal enhancer for niacinamide in Strat-M TM membranes E. Petrov, A. Verkhovskiy
Material type:
ArticleContent type: Текст Media type: электронный Subject(s): ксенон | ниацинамид | кожа | усилители трансдермальной абсорбции | Франца ячейка | трансдермальные системы доставки лекарстваGenre/Form: статьи в журналах Online resources: Click here to access online
In:
Medical gas research Vol. 12, № 1. P. 24-27Abstract: Xenon is confirmed to diffuse readily through membranes and has properties of transdermal enhancer. In this study, the ability of xenon to regulate the transdermal diffusion of niacinamide was investigated using a model of an artificial skin analogue of Strat-M (TM) membranes in Franz cells. Based on the data obtained, we found that in the simplified biophysical model of Strat-M (TM) membranes xenon exerts its enhancer effect based on the heterogeneous nucleation of xenon at the interfaces in the microporous structures of Strat-M (TM) membranes.
Библиогр.: 32 назв.
Xenon is confirmed to diffuse readily through membranes and has properties of transdermal enhancer. In this study, the ability of xenon to regulate the transdermal diffusion of niacinamide was investigated using a model of an artificial skin analogue of Strat-M (TM) membranes in Franz cells. Based on the data obtained, we found that in the simplified biophysical model of Strat-M (TM) membranes xenon exerts its enhancer effect based on the heterogeneous nucleation of xenon at the interfaces in the microporous structures of Strat-M (TM) membranes.
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