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Research on lymphedema by method of high-resolution multiphoton microscopy V. V. Nikolaev, O. S. Kurochkina, D. A. Vrazhnov [et al.]

Contributor(s): Kurochkina, Oksana S | Vrazhnov, Denis A | Sandykova, Ekaterina A | Kistenev, Yury V | Nikolaev, Viktor VMaterial type: ArticleArticleSubject(s): лимфедема | многофотонная микроскопия | автофлуоресценция | лимфатическая системаGenre/Form: статьи в журналах Online resources: Click here to access online In: Journal of Physics: Conference Series Vol. 1145. P. 012043 (1-6)Abstract: In this paper results of iv-vivo measurements for healthy volunteers and people, with verified diagnosis of lymphedema, obtained with two-photon tomography with fluorescence lifetime imaging microscopy (FLIM) are presented. The papillary layer of the skin was analyzed at a depth of about 100 μm. The purpose of this study is to evaluate the lifetime of autofluorescence in the papillary dermis of healthy tissue and with the initial stage of lymphedema. In the course of the study, a small redistribution of autofluorescence lifetimes was observed for healthy volunteers and people with lymphedema disease. The research was carried out on the equipment of MPTflex (JenLab GmbH).
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In this paper results of iv-vivo measurements for healthy volunteers and people, with verified diagnosis of lymphedema, obtained with two-photon tomography with fluorescence lifetime imaging microscopy (FLIM) are presented. The papillary layer of the skin was analyzed at a depth of about 100 μm. The purpose of this study is to evaluate the lifetime of autofluorescence in the papillary dermis of healthy tissue and with the initial stage of lymphedema. In the course of the study, a small redistribution of autofluorescence lifetimes was observed for healthy volunteers and people with lymphedema disease. The research was carried out on the equipment of MPTflex (JenLab GmbH).

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